Перегляд за Автор "Prystupa, Liudmyla"

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  • Документ
    BCL1 polymorphism of glucocorticoids receptor gene and bronchial asthma
    (2015) Kmyta, Vladyslava; Orlovskyi, Viktor; Prystupa, Liudmyla; Prystupa, Evhen; Кмита, Владислава; Орловський, Віктор; Приступа, Людмила; Приступа, Євген
    We have identified statistically significant differences in genotypes distribution of BclI polymorphism of GR gene in the control group and in patients with BA , homozygous for the minor allele had a higher risk of the disease than the major allele carriers. It was found out that G/G - homozygotes have a fivefold higher risk of BA, than those homozygous for C/C regardless of gender. We demonstrated that BA risk in females, homozygous for the minor allele, is three times higher and in males – 11,3 times higher, as compared with С/С - homozygotes. That is, men with G/G genotype of Bcl1 GR gene polymorphism have the highest risk of BA.