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Title: BCL1 polymorphism of glucocorticoids receptor gene and bronchial asthma
Authors: Kmyta, Vladyslava
Orlovskyi, Viktor
Prystupa, Liudmyla
Prystupa, Evhen
Кмита, Владислава
Орловський, Віктор
Приступа, Людмила
Приступа, Євген
Keywords: Bcl1 polymorphism
glucocorticoid receptor gene
bronchial asthma
Issue Date: 2015
Citation: BCL1 polymorphism of glucocorticoids receptor gene and bronchial asthma / Kmyta V. V., Orlovskyi V. F. , Prystupa L. N. , Prystupa E. N. // Georgial Medical News. – 2015. – № 3( 2040). – P. 51 - 55.
Abstract: We have identified statistically significant differences in genotypes distribution of BclI polymorphism of GR gene in the control group and in patients with BA , homozygous for the minor allele had a higher risk of the disease than the major allele carriers. It was found out that G/G - homozygotes have a fivefold higher risk of BA, than those homozygous for C/C regardless of gender. We demonstrated that BA risk in females, homozygous for the minor allele, is three times higher and in males – 11,3 times higher, as compared with С/С - homozygotes. That is, men with G/G genotype of Bcl1 GR gene polymorphism have the highest risk of BA.
Appears in Collections:Наукові праці професорсько-викладацького складу ЛДУФК в базах даних Scopus, WoS, Tomson Reuters

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